CONFIG_ISS4xx is not available for thedefaultarchitecture x86.
Result is shown for architecture powerpc

ISS 4xx Simulator

modulename: iss4xx.ko

configname: CONFIG_ISS4xx

Linux Kernel Configuration
└─>ISS 4xx Simulator
In linux kernel since version 2.6.35 (release Date: 2010-08-01)  
This option enables support for the IBM ISS simulation environment

source code:
arch/powerpc/platforms/44x/iss4xx.c

depends
CONFIG_40x or CONFIG_44x